37 kDa LRP::FLAG enhances telomerase activity and reduces senescent markers in vitro

One of the core regulators of cellular aging are telomeres, repetitive DNA sequences at the ends of chromosomes that are maintained by the ribonucleoprotein DNA polymerase complex, telomerase. Recently, we demonstrated that knockdown of the 37kDa/ 67kDa laminin receptor (LRP/LR), a protein that prom...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Otgaar, Tyrone C., Ferreira, Eloise, Malindisa, Sibusiso, Bernert, Martin, Letsolo, Boitelo T., Weiss, Stefan F.T.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689714/
https://ncbi.nlm.nih.gov/pubmed/29156824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21278
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