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Codon optimization significantly enhanced the expression of human 37-kDa iLRP in Escherichia coli

37-kDa immature laminin receptor protein (iLRP), the precursor of 67-kDa laminin receptor protein (LRP), is overexpressed on the surface of most cancer cells and recognized as a universal tumor antigen. The role makes it a potential target for cancer immunotherapy, which has been well-studied. Our s...

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Detalhes bibliográficos
Publicado no:3 Biotech
Main Authors: Liu, Bainan, Kong, Qianqian, Zhang, Dong, Yan, Lingli
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889372/
https://ncbi.nlm.nih.gov/pubmed/29651375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-018-1234-y
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