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Complex repeat structure promotes hyper-amplification and amplicon evolution through rolling-circle replication
Inverted repeats (IRs) are abundant in genomes and frequently serve as substrates for chromosomal aberrations, including gene amplification. In the early stage of amplification, repeated cycles of chromosome breakage and rearrangement, called breakage-fusion-bridge (BFB), generate a large inverted s...
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| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6007334/ https://ncbi.nlm.nih.gov/pubmed/29718479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky275 |
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