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A novel gene amplification system in yeast based on double rolling-circle replication

Gene amplification is involved in various biological phenomena such as cancer development and drug resistance. However, the mechanism is largely unknown because of the complexity of the amplification process. We describe a gene amplification system in Saccharomyces cerevisiae that is based on double...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Watanabe, Takaaki, Horiuchi, Takashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC544915/
https://ncbi.nlm.nih.gov/pubmed/15616589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600503
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