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A novel gene amplification system in yeast based on double rolling-circle replication

Gene amplification is involved in various biological phenomena such as cancer development and drug resistance. However, the mechanism is largely unknown because of the complexity of the amplification process. We describe a gene amplification system in Saccharomyces cerevisiae that is based on double...

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Bibliographic Details
Main Authors: Watanabe, Takaaki, Horiuchi, Takashi
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC544915/
https://ncbi.nlm.nih.gov/pubmed/15616589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600503
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