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Immunotherapy to improve cognition and reduce pathological species in an Alzheimer’s disease mouse model
BACKGROUND: Alzheimer’s disease (AD) is characterized by physiologically endogenous proteins amyloid beta (Aβ) and tau undergoing a conformational change and accumulating as soluble oligomers and insoluble aggregates. Tau and Aβ soluble oligomers, which contain extensive β-sheet secondary structure,...
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| Publicado no: | Alzheimers Res Ther |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6006698/ https://ncbi.nlm.nih.gov/pubmed/29914551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-018-0384-9 |
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