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A pharmacological rationale for improved everolimus dosing in oncology and transplant patients

AIMS: Everolimus is a drug from the class of mammalian target of rapamycin inhibitors used for both immunosuppressant and oncological indications. We postulate that there is room for improvement of dosing, as the optimal immunosuppressive dose in calcineurin‐free regimens is unknown and since the on...

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Publicat a:Br J Clin Pharmacol
Autors principals: ter Heine, R., van Erp, N. P., Guchelaar, H. J., de Fijter, J. W., Reinders, M. E. J., van Herpen, C. M., Burger, D. M., Moes, D. J. A. R.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005589/
https://ncbi.nlm.nih.gov/pubmed/29574974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13591
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