Model-Informed Precision Dosing of Everolimus: External Validation in Adult Renal Transplant Recipients

BACKGROUND AND OBJECTIVE: The immunosuppressant everolimus is increasingly applied in renal transplantation. Its extensive pharmacokinetic variability necessitates therapeutic drug monitoring, typically based on whole-blood trough concentrations (C(0)). Unfortunately, therapeutic drug monitoring tar...

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Detalhes bibliográficos
Publicado no:Clin Pharmacokinet
Main Authors: Zwart, Tom C., Moes, Dirk Jan A. R., van der Boog, Paul J. M., van Erp, Nielka P., de Fijter, Johan W., Guchelaar, Henk-Jan, Keizer, Ron J., ter Heine, Rob
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
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Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862213/
https://ncbi.nlm.nih.gov/pubmed/32720301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-020-00925-8
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