Defining cancer subpopulations by adaptive strategies rather than molecular properties provides novel insights into intratumoral evolution

Ongoing intratumoral evolution is apparent in molecular variations among cancer cells from different regions of the same tumor, but genetic data alone provide little insight into environmental selection forces and cellular phenotypic adaptations that govern the underlying Darwinian dynamics. In thre...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Ibrahim-Hashim, Arig, Robertson-Tessi, Mark, Enriquez-Navas, Pedro M., Damaghi, Mehdi, Balagurunathan, Yoganand, Wojtkowiak, Jonathan W., Russell, Shonagh, Kam, Yoonseok, Lloyd, Mark C., Bui, Marilyn, Brown, Joel, Anderson, Alexander R. A., Gillies, Robert J, Gatenby, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005351/
https://ncbi.nlm.nih.gov/pubmed/28249898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-2844
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