Heme redox potentials hold the key to reactivity differences between nitric oxide reductase and heme-copper oxidase

Despite high structural homology between NO reductases (NORs) and heme-copper oxidases (HCOs), factors governing their reaction specificity remain to be understood. Using a myoglobin-based model of NOR (Fe(B)Mb) and tuning its heme redox potentials (E°′) to cover the native NOR range, through manipu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Bhagi-Damodaran, Ambika, Reed, Julian H., Zhu, Qianhong, Shi, Yelu, Hosseinzadeh, Parisa, Sandoval, Braddock A., Harnden, Kevin A., Wang, Shuyan, Sponholtz, Madeline R., Mirts, Evan N., Dwaraknath, Sudharsan, Zhang, Yong, Moënne-Loccoz, Pierre, Lu, Yi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2018
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004492/
https://ncbi.nlm.nih.gov/pubmed/29802230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720298115
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg