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Heme redox potentials hold the key to reactivity differences between nitric oxide reductase and heme-copper oxidase
Despite high structural homology between NO reductases (NORs) and heme-copper oxidases (HCOs), factors governing their reaction specificity remain to be understood. Using a myoglobin-based model of NOR (Fe(B)Mb) and tuning its heme redox potentials (E°′) to cover the native NOR range, through manipu...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6004492/ https://ncbi.nlm.nih.gov/pubmed/29802230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720298115 |
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