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Why copper is preferred over iron for oxygen activation and reduction in heme-copper oxidases

Heme-copper oxidase (HCO) catalyzes the natural reduction of oxygen to water using a heme-copper center. Despite decades of research on HCO's, the role of nonheme metal and Nature's choice of copper over other metals like iron remains unclear. Here, we use a biosynthetic model of HCO in my...

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Detalhes bibliográficos
Publicado no:Nat Chem
Main Authors: Bhagi-Damodaran, Ambika, Michael, Matthew A., Zhu, Qianhong, Reed, Julian, Sandoval, Braddock A., Mirts, Evan N., Chakraborty, Saumen, Moënne-Loccoz, Pierre, Zhang, Yong, Lu, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321616/
https://ncbi.nlm.nih.gov/pubmed/28221360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2643
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