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Effect of outer-sphere side chain substitutions on the fate of the trans iron-nitrosyl dimer in heme/nonheme engineered myoglobins (Fe(B)Mbs): Insights into the mechanism of denitrifying NO reductases

Denitrifying NO reductases are transmembrane protein complexes that utilize a heme/nonheme diiron center at their active sites to reduce two NO molecules to the innocuous gas N(2)O. Fe(B)Mb proteins, with their nonheme iron sites engineered into the heme distal pocket of sperm whale myoglobin, are a...

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Detalles Bibliográficos
Publicado en:Biochemistry
Autores principales: Matsumura, Hirotoshi, Chakraborty, Saumen, Reed, Julian, Lu, Yi, Moënne-Loccoz, Pierre
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5181652/
https://ncbi.nlm.nih.gov/pubmed/27003474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01109
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