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Effect of outer-sphere side chain substitutions on the fate of the trans iron-nitrosyl dimer in heme/nonheme engineered myoglobins (Fe(B)Mbs): Insights into the mechanism of denitrifying NO reductases

Denitrifying NO reductases are transmembrane protein complexes that utilize a heme/nonheme diiron center at their active sites to reduce two NO molecules to the innocuous gas N(2)O. Fe(B)Mb proteins, with their nonheme iron sites engineered into the heme distal pocket of sperm whale myoglobin, are a...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Matsumura, Hirotoshi, Chakraborty, Saumen, Reed, Julian, Lu, Yi, Moënne-Loccoz, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5181652/
https://ncbi.nlm.nih.gov/pubmed/27003474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01109
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