NT3-chitosan enables de novo regeneration and functional recovery in monkeys after spinal cord injury

Spinal cord injury (SCI) often leads to permanent loss of motor, sensory, and autonomic functions. We have previously shown that neurotrophin3 (NT3)-loaded chitosan biodegradable material allowed for prolonged slow release of NT3 for 14 weeks under physiological conditions. Here we report that NT3-l...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Proc Natl Acad Sci U S A
Κύριοι συγγραφείς: Rao, Jia-Sheng, Zhao, Can, Zhang, Aifeng, Duan, Hongmei, Hao, Peng, Wei, Rui-Han, Shang, Junkui, Zhao, Wen, Liu, Zuxiang, Yu, Juehua, Fan, Kevin S., Tian, Zhaolong, He, Qihua, Song, Wei, Yang, Zhaoyang, Sun, Yi Eve, Li, Xiaoguang
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2018
Θέματα:
PNAS Plus
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004491/
https://ncbi.nlm.nih.gov/pubmed/29844162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804735115
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