NT3-chitosan enables de novo regeneration and functional recovery in monkeys after spinal cord injury

Spinal cord injury (SCI) often leads to permanent loss of motor, sensory, and autonomic functions. We have previously shown that neurotrophin3 (NT3)-loaded chitosan biodegradable material allowed for prolonged slow release of NT3 for 14 weeks under physiological conditions. Here we report that NT3-l...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Rao, Jia-Sheng, Zhao, Can, Zhang, Aifeng, Duan, Hongmei, Hao, Peng, Wei, Rui-Han, Shang, Junkui, Zhao, Wen, Liu, Zuxiang, Yu, Juehua, Fan, Kevin S., Tian, Zhaolong, He, Qihua, Song, Wei, Yang, Zhaoyang, Sun, Yi Eve, Li, Xiaoguang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004491/
https://ncbi.nlm.nih.gov/pubmed/29844162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804735115
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