NT3-chitosan enables de novo regeneration and functional recovery in monkeys after spinal cord injury

Spinal cord injury (SCI) often leads to permanent loss of motor, sensory, and autonomic functions. We have previously shown that neurotrophin3 (NT3)-loaded chitosan biodegradable material allowed for prolonged slow release of NT3 for 14 weeks under physiological conditions. Here we report that NT3-l...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Rao, Jia-Sheng, Zhao, Can, Zhang, Aifeng, Duan, Hongmei, Hao, Peng, Wei, Rui-Han, Shang, Junkui, Zhao, Wen, Liu, Zuxiang, Yu, Juehua, Fan, Kevin S., Tian, Zhaolong, He, Qihua, Song, Wei, Yang, Zhaoyang, Sun, Yi Eve, Li, Xiaoguang
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004491/
https://ncbi.nlm.nih.gov/pubmed/29844162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804735115
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