Sustained adrenergic signaling promotes intratumoral innervation through BDNF induction

Mounting clinical and preclinical evidence supports a key role for sustained adrenergic signaling in the tumor microenvironment as a driver of tumor growth and progression. However, the mechanisms by which adrenergic neurotransmitters are delivered to the tumor microenvironment are not well understo...

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發表在:Cancer Res
Main Authors: Allen, Julie K., Armaiz-Pena, Guillermo N., Nagaraja, Archana S., Sadaoui, Nouara C., Ortiz, Tatiana, Dood, Robert, Ozcan, Merve, Herder, Danielle M., Haemerrle, Monika, Gharpure, Kshipra M., Rupaimoole, Rajesha, Previs, Rebecca A., Wu, Sherry Y., Pradeep, Sunila, Xu, Xiaoyun, Han, Hee Dong, Zand, Behrouz, Dalton, Heather J., Taylor, Morgan, Hu, Wei, Bottsford-Miller, Justin, Moreno-Smith, Myrthala, Kang, Yu, Mangala, Lingegowda S., Rodriguez-Aguayo, Cristian, Sehgal, Vasudha, Spaeth, Erika L., Ram, Prahlad T., Wong, Stephen T.C., Marini, Frank C., Lopez-Berestein, Gabriel, Cole, Steve W., Lutgendorf, Susan K., De Biasi, Mariella, Sood, Anil K.
格式: Artigo
語言:Inglês
出版: 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004256/
https://ncbi.nlm.nih.gov/pubmed/29661830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1701
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