Adrenergic stimulation of DUSP1 impairs chemotherapy response in ovarian cancer

PURPOSE: Chronic adrenergic activation has been shown to associate with adverse clinical outcomes in cancer patients, but the underlying mechanisms are not well understood. The focus of the current study was to determine the functional and biological effects of adrenergic pathways on response to che...

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Publicat a:Clin Cancer Res
Autors principals: Kang, Yu, Nagaraja, Archana S., Armaiz-Pena, Guillermo N., Dorniak, Piotr L., Hu, Wei, Rupaimoole, Rajesha, Liu, Tao, Gharpure, Kshipra M., Previs, Rebecca A., Hansen, Jean M., Rodriguez-Aguayo, Cristian, Ivan, Cristina, Ram, Prahlad, Sehgal, Vasudha, Lopez-Berestein, Gabriel, Lutgendorf, Susan K., Cole, Steven W., Sood, Anil K.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818718/
https://ncbi.nlm.nih.gov/pubmed/26581245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1275
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