Adrenergic stimulation of DUSP1 impairs chemotherapy response in ovarian cancer

PURPOSE: Chronic adrenergic activation has been shown to associate with adverse clinical outcomes in cancer patients, but the underlying mechanisms are not well understood. The focus of the current study was to determine the functional and biological effects of adrenergic pathways on response to che...

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Gepubliceerd in:Clin Cancer Res
Hoofdauteurs: Kang, Yu, Nagaraja, Archana S., Armaiz-Pena, Guillermo N., Dorniak, Piotr L., Hu, Wei, Rupaimoole, Rajesha, Liu, Tao, Gharpure, Kshipra M., Previs, Rebecca A., Hansen, Jean M., Rodriguez-Aguayo, Cristian, Ivan, Cristina, Ram, Prahlad, Sehgal, Vasudha, Lopez-Berestein, Gabriel, Lutgendorf, Susan K., Cole, Steven W., Sood, Anil K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818718/
https://ncbi.nlm.nih.gov/pubmed/26581245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1275
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