Adrenergic stimulation of DUSP1 impairs chemotherapy response in ovarian cancer

PURPOSE: Chronic adrenergic activation has been shown to associate with adverse clinical outcomes in cancer patients, but the underlying mechanisms are not well understood. The focus of the current study was to determine the functional and biological effects of adrenergic pathways on response to che...

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Détails bibliographiques
Publié dans:Clin Cancer Res
Auteurs principaux: Kang, Yu, Nagaraja, Archana S., Armaiz-Pena, Guillermo N., Dorniak, Piotr L., Hu, Wei, Rupaimoole, Rajesha, Liu, Tao, Gharpure, Kshipra M., Previs, Rebecca A., Hansen, Jean M., Rodriguez-Aguayo, Cristian, Ivan, Cristina, Ram, Prahlad, Sehgal, Vasudha, Lopez-Berestein, Gabriel, Lutgendorf, Susan K., Cole, Steven W., Sood, Anil K.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818718/
https://ncbi.nlm.nih.gov/pubmed/26581245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1275
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