Adrenergic-mediated increases in INHBA drive CAF phenotype and collagens

Adrenergic signaling is known to promote tumor growth and metastasis, but the effects on tumor stroma are not well understood. An unbiased bioinformatics approach analyzing tumor samples from patients with known biobehavioral profiles identified a prominent stromal signature associated with cancer-a...

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Bibliografiset tiedot
Julkaisussa:JCI Insight
Päätekijät: Nagaraja, Archana S., Dood, Robert L., Armaiz-Pena, Guillermo, Kang, Yu, Wu, Sherry Y., Allen, Julie K., Jennings, Nicholas B., Mangala, Lingegowda S., Pradeep, Sunila, Lyons, Yasmin, Haemmerle, Monika, Gharpure, Kshipra M., Sadaoui, Nouara C., Rodriguez-Aguayo, Cristian, Ivan, Cristina, Wang, Ying, Baggerly, Keith, Ram, Prahlad, Lopez-Berestein, Gabriel, Liu, Jinsong, Mok, Samuel C., Cohen, Lorenzo, Lutgendorf, Susan K., Cole, Steve W., Sood, Anil K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2017
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621917/
https://ncbi.nlm.nih.gov/pubmed/28814667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93076
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