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SRSF3 recruits DROSHA to the basal junction of primary microRNAs
The Microprocessor complex, consisting of an RNase III DROSHA and the DGCR8 dimer, cleaves primary microRNA transcripts (pri-miRNAs) to initiate microRNA (miRNA) maturation. Pri-miRNAs are stem–loop RNAs, and ∼79% of them contain at least one of the three major and conserved RNA motifs, UG, UGU, and...
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| Pubblicato in: | RNA |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6004053/ https://ncbi.nlm.nih.gov/pubmed/29615481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.065862.118 |
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