Identification of near pan-neutralizing antibodies against HIV-1 by deconvolution of plasma humoral responses

Anti-HIV-1 envelope broadly neutralizing monoclonal antibodies (bNAbs) isolated from memory B-cells may not fully represent HIV-1 neutralizing profiles measured in plasma. Accordingly, we characterized near pan-neutralizing antibodies extracted directly from the plasma of two “elite neutralizers.” C...

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Veröffentlicht in:Cell
Hauptverfasser: Sajadi, Mohammad Mohseni, Dashti, Amir, Tehrani, Zahra Rikhtegaran, Tolbert, William D., Seaman, Michael S., Ouyang, Xin, Gohain, Neelakshi, Pazgier, Marzena, Kim, Dongkyoon, Cavet, Guy, Yared, Jean, Redfield, Robert R., Lewis, George K., DeVico, Anthony L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003858/
https://ncbi.nlm.nih.gov/pubmed/29731169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.03.061
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