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Conformational Masking and Receptor-Dependent Unmasking of Highly Conserved Env Epitopes Recognized by Non-Neutralizing Antibodies That Mediate Potent ADCC against HIV-1

The mechanism of antibody-mediated protection is a major focus of HIV-1 vaccine development and a significant issue in the control of viremia. Virus neutralization, Fc-mediated effector function, or both, are major mechanisms of antibody-mediated protection against HIV-1, although other mechanisms,...

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Bibliografski detalji
Izdano u:Viruses
Glavni autori: Lewis, George K., Finzi, Andrés, DeVico, Anthony L., Pazgier, Marzena
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584300/
https://ncbi.nlm.nih.gov/pubmed/26393642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7092856
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