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HIV anti-latency treatment mediated by macromolecular prodrugs of histone deacetylase inhibitor, panobinostat

Histone deacetylase inhibitors (HDACi) and panobinostat in particular are currently in the focus of intensive investigation as latency reversing agents against the human immunodeficiency virus (HIV). Regretfully, HDACi have dose limiting side-effects making controlled, optimized methods for delivery...

詳細記述

保存先:
書誌詳細
出版年:Chem Sci
主要な著者: Zuwala, Kaja, Smith, Anton A. A., Tolstrup, Martin, Zelikin, Alexander N.
フォーマット: Artigo
言語:Inglês
出版事項: Royal Society of Chemistry 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003675/
https://ncbi.nlm.nih.gov/pubmed/29997778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc03257a
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