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Inverted allosteric coupling between activation and inactivation gates in K(+) channels
The selectivity filter and the activation gate in potassium channels are functionally and structurally coupled. An allosteric coupling underlies C-type inactivation coupled to activation gating in this ion-channel family (i.e., opening of the activation gate triggers the collapse of the channel’s se...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6003467/ https://ncbi.nlm.nih.gov/pubmed/29735651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1800559115 |
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