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The gating cycle of a K(+) channel at atomic resolution

C-type inactivation in potassium channels helps fine-tune long-term channel activity through conformational changes at the selectivity filter. Here, through the use of cross-linked constitutively open constructs, we determined the structures of KcsA’s mutants that stabilize the selectivity filter in...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Cuello, Luis G, Cortes, D Marien, Perozo, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711375/
https://ncbi.nlm.nih.gov/pubmed/29165243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28032
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