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Structural mechanism of C-type inactivation in K(+) channels

Interconversion between conductive and non-conductive forms of the K(+) channel selectivity filter underlies a variety of gating events, from flicker transitions (μs) to C-type inactivation (ms-s). Here, we report the crystal structure of the K(+) channel KcsA in its Open-Inactivated conformation an...

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Detalhes bibliográficos
Main Authors: Cuello, Luis G., Jogini, Vishwanath, Cortes, D. Marien, Perozo, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033749/
https://ncbi.nlm.nih.gov/pubmed/20613835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09153
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