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On The Structural Basis of Modal Gating Behavior in K(+) Channels

Modal-gating shifts represent an effective regulatory mechanism by which ion channels control the extent and time course of ionic fluxes. Under steady-state conditions, the K(+) channel KcsA displays three distinct gating modes, high-P(o), low-P(o) and a high-frequency flicker mode, each with about...

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Detalhes bibliográficos
Main Authors: Chakrapani, Sudha, Cordero-Morales, Julio F., Jogini, Vishwanath, Pan, Albert C., Cortes, D. Marien, Roux, Benoît, Perozo, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059741/
https://ncbi.nlm.nih.gov/pubmed/21186363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1968
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