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Recovery from Slow Inactivation in K(+) Channels is Controlled by Water Molecules

The bacterial K(+) channel KcsA can be used to help elucidate questions about channel inactivation and recovery at the atomic level. Although KcsA contains only a pore domain, without voltage-sensing machinery, it has the structural elements necessary for ion conduction, activation and inactivation(...

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Detalhes bibliográficos
Main Authors: Ostmeyer, Jared, Chakrapani, Sudha, Pan, Albert C., Perozo, Eduardo, Roux, Benoît
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799803/
https://ncbi.nlm.nih.gov/pubmed/23892782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12395
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