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Structural basis for the coupling between activation and inactivation gates in K(+) channels
The coupled interplay between activation and inactivation gating is a functional hallmark of K(+) channels1,2. This coupling has been experimentally demonstrated from ion interaction effects3,4, cysteine accessibility1 and is associated with a well-defined boundary of energetically coupled residues2...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033755/ https://ncbi.nlm.nih.gov/pubmed/20613845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09136 |
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