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Riboswitches for the alarmone ppGpp expand the collection of RNA-based signaling systems

Riboswitches are noncoding portions of certain mRNAs that bind metabolite, coenzyme, signaling molecule, or inorganic ion ligands and regulate gene expression. Most known riboswitches sense derivatives of RNA monomers. This bias in ligand chemical composition is consistent with the hypothesis that w...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sherlock, Madeline E., Sudarsan, Narasimhan, Breaker, Ronald R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003355/
https://ncbi.nlm.nih.gov/pubmed/29784782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720406115
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