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Riboswitches for the alarmone ppGpp expand the collection of RNA-based signaling systems

Riboswitches are noncoding portions of certain mRNAs that bind metabolite, coenzyme, signaling molecule, or inorganic ion ligands and regulate gene expression. Most known riboswitches sense derivatives of RNA monomers. This bias in ligand chemical composition is consistent with the hypothesis that w...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Sherlock, Madeline E., Sudarsan, Narasimhan, Breaker, Ronald R.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003355/
https://ncbi.nlm.nih.gov/pubmed/29784782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720406115
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