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Riboswitches for the alarmone ppGpp expand the collection of RNA-based signaling systems

Riboswitches are noncoding portions of certain mRNAs that bind metabolite, coenzyme, signaling molecule, or inorganic ion ligands and regulate gene expression. Most known riboswitches sense derivatives of RNA monomers. This bias in ligand chemical composition is consistent with the hypothesis that w...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Sherlock, Madeline E., Sudarsan, Narasimhan, Breaker, Ronald R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003355/
https://ncbi.nlm.nih.gov/pubmed/29784782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720406115
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