WNK1 regulates skeletal muscle cell hypertrophy by modulating the nuclear localization and transcriptional activity of FOXO4

With-no-lysine (K) (WNK) kinases, which are mutated in the inherited form of hypertension pseudohypoaldosteronism type II, are essential regulators of membrane ion transporters. Here, we report that WNK1 positively regulates skeletal muscle cell hypertrophy via mediating the function of the pro-long...

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Publicat a:Sci Rep
Autors principals: Mandai, Shintaro, Mori, Takayasu, Nomura, Naohiro, Furusho, Taisuke, Arai, Yohei, Kikuchi, Hiroaki, Sasaki, Emi, Sohara, Eisei, Rai, Tatemitsu, Uchida, Shinichi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002401/
https://ncbi.nlm.nih.gov/pubmed/29904119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27414-0
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