Loop diuretics affect skeletal myoblast differentiation and exercise-induced muscle hypertrophy

Muscle wasting or sarcopenia contributes to morbidity and mortality in patients with cancer, renal failure, or heart failure, and in elderly individuals. Na(+)-K(+)-2Cl(−) cotransporter 1 (NKCC1) is highly expressed in mammalian skeletal muscle, where it contributes to the generation of membrane ion...

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Pubblicato in:Sci Rep
Autori principali: Mandai, Shintaro, Furukawa, Susumu, Kodaka, Manami, Hata, Yutaka, Mori, Takayasu, Nomura, Naohiro, Ando, Fumiaki, Mori, Yutaro, Takahashi, Daiei, Yoshizaki, Yuki, Kasagi, Yuri, Arai, Yohei, Sasaki, Emi, Yoshida, Sayaka, Furuichi, Yasuro, Fujii, Nobuharu L., Sohara, Eisei, Rai, Tatemitsu, Uchida, Shinichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394462/
https://ncbi.nlm.nih.gov/pubmed/28417963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46369
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