WNK1 regulates skeletal muscle cell hypertrophy by modulating the nuclear localization and transcriptional activity of FOXO4

With-no-lysine (K) (WNK) kinases, which are mutated in the inherited form of hypertension pseudohypoaldosteronism type II, are essential regulators of membrane ion transporters. Here, we report that WNK1 positively regulates skeletal muscle cell hypertrophy via mediating the function of the pro-long...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mandai, Shintaro, Mori, Takayasu, Nomura, Naohiro, Furusho, Taisuke, Arai, Yohei, Kikuchi, Hiroaki, Sasaki, Emi, Sohara, Eisei, Rai, Tatemitsu, Uchida, Shinichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002401/
https://ncbi.nlm.nih.gov/pubmed/29904119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27414-0
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