KLHL3 Knockout Mice Reveal the Physiological Role of KLHL3 and the Pathophysiology of Pseudohypoaldosteronism Type II Caused by Mutant KLHL3

Mutations in the with-no-lysine kinase 1 (WNK1), WNK4, kelch-like 3 (KLHL3), and cullin3 (CUL3) genes are known to cause the hereditary disease pseudohypoaldosteronism type II (PHAII). It was recently demonstrated that this results from the defective degradation of WNK1 and WNK4 by the KLHL3/CUL3 ub...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Sasaki, Emi, Susa, Koichiro, Mori, Takayasu, Isobe, Kiyoshi, Araki, Yuya, Inoue, Yuichi, Yoshizaki, Yuki, Ando, Fumiaki, Mori, Yutaro, Mandai, Shintaro, Zeniya, Moko, Takahashi, Daiei, Nomura, Naohiro, Rai, Tatemitsu, Uchida, Shinichi, Sohara, Eisei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359427/
https://ncbi.nlm.nih.gov/pubmed/28052936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00508-16
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