Kelch-Like Protein 2 Mediates Angiotensin II–With No Lysine 3 Signaling in the Regulation of Vascular Tonus

Recently, the kelch-like protein 3 (KLHL3)–Cullin3 complex was identified as an E3 ubiquitin ligase for with no lysine (WNK) kinases, and the impaired ubiquitination of WNK4 causes pseudohypoaldosteronism type II (PHAII), a hereditary hypertensive disease. However, the involvement of WNK kinase regu...

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Veröffentlicht in:J Am Soc Nephrol
Hauptverfasser: Zeniya, Moko, Morimoto, Nobuhisa, Takahashi, Daiei, Mori, Yutaro, Mori, Takayasu, Ando, Fumiaki, Araki, Yuya, Yoshizaki, Yuki, Inoue, Yuichi, Isobe, Kiyoshi, Nomura, Naohiro, Oi, Katsuyuki, Nishida, Hidenori, Sasaki, Sei, Sohara, Eisei, Rai, Tatemitsu, Uchida, Shinichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2015
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552111/
https://ncbi.nlm.nih.gov/pubmed/25556166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014070639
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