Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis

AIM: Rheumatoid arthritis (RA) is associated with an approximately two-fold elevated risk of cardiovascular (CV)-related mortality. Patients with RA present with systemic inflammation including raised circulating myeloid cells, but fail to display traditional CV risk-factors, particularly dyslipidae...

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Detalhes bibliográficos
Publicado no:Eur Heart J
Main Authors: Dragoljevic, Dragana, Kraakman, Michael J, Nagareddy, Prabhakara R, Ngo, Devi, Shihata, Waled, Kammoun, Helene L, Whillas, Alexandra, Lee, Man Kit Sam, Al-Sharea, Annas, Pernes, Gerard, Flynn, Michelle C, Lancaster, Graeme I, Febbraio, Mark A, Chin-Dusting, Jaye, Hanaoka, Beatriz Y, Wicks, Ian P, Murphy, Andrew J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001889/
https://ncbi.nlm.nih.gov/pubmed/29905812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehy119
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