Inhibition of interleukin‐1β signalling promotes atherosclerotic lesion remodelling in mice with inflammatory arthritis

OBJECTIVES: Rheumatoid arthritis (RA), an inflammatory joint disorder, independently increases the risk of cardiovascular disease (CVD). IL‐1β contributes to both RA and CVD. We hypothesised that inhibiting IL‐1 signalling with the IL‐1R antagonist, anakinra, would dampen inflammation and promote re...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Clin Transl Immunology
Autori principali: Dragoljevic, Dragana, Lee, Man Kit Sam, Louis, Cynthia, Shihata, Waled, Kraakman, Michael J, Hansen, Jacinta, Masters, Seth L, Hanaoka, Beatriz Y, Nagareddy, Prabhakara R, Lancaster, Graeme I, Wicks, Ian P, Murphy, Andrew J
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
Soggetti:
Short Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652637/
https://ncbi.nlm.nih.gov/pubmed/33204425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1206
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi