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Inhibition of interleukin‐1β signalling promotes atherosclerotic lesion remodelling in mice with inflammatory arthritis

OBJECTIVES: Rheumatoid arthritis (RA), an inflammatory joint disorder, independently increases the risk of cardiovascular disease (CVD). IL‐1β contributes to both RA and CVD. We hypothesised that inhibiting IL‐1 signalling with the IL‐1R antagonist, anakinra, would dampen inflammation and promote re...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Dragoljevic, Dragana, Lee, Man Kit Sam, Louis, Cynthia, Shihata, Waled, Kraakman, Michael J, Hansen, Jacinta, Masters, Seth L, Hanaoka, Beatriz Y, Nagareddy, Prabhakara R, Lancaster, Graeme I, Wicks, Ian P, Murphy, Andrew J
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652637/
https://ncbi.nlm.nih.gov/pubmed/33204425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1206
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