Inhibition of interleukin‐1β signalling promotes atherosclerotic lesion remodelling in mice with inflammatory arthritis

OBJECTIVES: Rheumatoid arthritis (RA), an inflammatory joint disorder, independently increases the risk of cardiovascular disease (CVD). IL‐1β contributes to both RA and CVD. We hypothesised that inhibiting IL‐1 signalling with the IL‐1R antagonist, anakinra, would dampen inflammation and promote re...

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Dades bibliogràfiques
Publicat a:Clin Transl Immunology
Autors principals: Dragoljevic, Dragana, Lee, Man Kit Sam, Louis, Cynthia, Shihata, Waled, Kraakman, Michael J, Hansen, Jacinta, Masters, Seth L, Hanaoka, Beatriz Y, Nagareddy, Prabhakara R, Lancaster, Graeme I, Wicks, Ian P, Murphy, Andrew J
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Short Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652637/
https://ncbi.nlm.nih.gov/pubmed/33204425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1206
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