Leptin-deficient obesity prolongs survival in a murine model of myelodysplastic syndrome

Obesity enhances the risk of developing myelodysplastic syndromes. However, the effect of obesity on survival is unclear. Obese people present with monocytosis due to inflammatory signals emanating from obese adipose tissue. We hypothesized that obesity-induced myelopoiesis would promote the transit...

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Dades bibliogràfiques
Publicat a:Haematologica
Autors principals: Kraakman, Michael J., Kammoun, Helene L., Dragoljevic, Dragana, Al-Sharea, Annas, Lee, Man K.S., Flynn, Michelle C., Stolz, Christian J., Guirguis, Andrew A., Lancaster, Graeme I., Chin-Dusting, Jaye, Curtis, David J., Murphy, Andrew J.
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865427/
https://ncbi.nlm.nih.gov/pubmed/29371326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.181958
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