Leptin-deficient obesity prolongs survival in a murine model of myelodysplastic syndrome

Obesity enhances the risk of developing myelodysplastic syndromes. However, the effect of obesity on survival is unclear. Obese people present with monocytosis due to inflammatory signals emanating from obese adipose tissue. We hypothesized that obesity-induced myelopoiesis would promote the transit...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Kraakman, Michael J., Kammoun, Helene L., Dragoljevic, Dragana, Al-Sharea, Annas, Lee, Man K.S., Flynn, Michelle C., Stolz, Christian J., Guirguis, Andrew A., Lancaster, Graeme I., Chin-Dusting, Jaye, Curtis, David J., Murphy, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865427/
https://ncbi.nlm.nih.gov/pubmed/29371326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.181958
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