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Identifying Small‐Molecule Binding Sites for Epigenetic Proteins at Domain–Domain Interfaces

Epigenetics is a rapidly growing field in drug discovery. Of particular interest is the role of post‐translational modifications to histones and the proteins that read, write, and erase such modifications. The development of inhibitors for reader domains has focused on single domains. One of the maj...

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Podrobná bibliografie
Vydáno v:ChemMedChem
Hlavní autoři: Bowkett, David, Talon, Romain, Tallant, Cynthia, Schofield, Chris, von Delft, Frank, Knapp, Stefan, Bruton, Gordon, Brennan, Paul E.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001751/
https://ncbi.nlm.nih.gov/pubmed/29578648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201800030
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