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Towards Ligand Docking Including Explicit Interface Water Molecules

Small molecule docking predicts the interaction of a small molecule ligand with a protein at atomic-detail accuracy including position and conformation the ligand but also conformational changes of the protein upon ligand binding. While successful in the majority of cases, docking algorithms includi...

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Hlavní autoři: Lemmon, Gordon, Meiler, Jens
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695863/
https://ncbi.nlm.nih.gov/pubmed/23840735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067536
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