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Computational design of protein-small molecule interfaces

The computational design of proteins that bind small molecule ligands is one of the unsolved challenges in protein engineering. It is complicated by the relatively small size of the ligand which limits the number of intermolecular interactions. Furthermore, near-perfect geometries between interactin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Allison, Brittany, Combs, Steven, DeLuca, Sam, Lemmon, Gordon, Mizoue, Laura, Meiler, Jens
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946393/
https://ncbi.nlm.nih.gov/pubmed/23962892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2013.08.003
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