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Computational design of protein-small molecule interfaces
The computational design of proteins that bind small molecule ligands is one of the unsolved challenges in protein engineering. It is complicated by the relatively small size of the ligand which limits the number of intermolecular interactions. Furthermore, near-perfect geometries between interactin...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3946393/ https://ncbi.nlm.nih.gov/pubmed/23962892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2013.08.003 |
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