Ultrasensitive Capture of Human Herpes Simplex Virus Genomes Directly from Clinical Samples Reveals Extraordinarily Limited Evolution in Cell Culture

Herpes simplex viruses (HSVs) are difficult to sequence due to their large DNA genome, high GC content, and the presence of repeats. To date, most HSV genomes have been recovered from culture isolates, raising concern that these genomes may not accurately represent circulating clinical strains. We r...

詳細記述

保存先:
書誌詳細
出版年:mSphere
主要な著者: Greninger, Alexander L., Roychoudhury, Pavitra, Xie, Hong, Casto, Amanda, Cent, Anne, Pepper, Gregory, Koelle, David M., Huang, Meei-Li, Wald, Anna, Johnston, Christine, Jerome, Keith R.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2018
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001610/
https://ncbi.nlm.nih.gov/pubmed/29898986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphereDirect.00283-18
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