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Aire controls the recirculation of murine Foxp3(+) regulatory T‐cells back to the thymus
In the thymus, medullary thymic epithelial cells (mTEC) determine the fate of newly selected CD4(+) and CD8(+) single positive (SP) thymocytes. For example, mTEC expression of Aire controls intrathymic self‐antigen availability for negative selection. Interestingly, alterations in both Foxp3(+) Regu...
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| Pubblicato in: | Eur J Immunol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6001551/ https://ncbi.nlm.nih.gov/pubmed/29285761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201747375 |
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