Differential Requirement for CCR4 and CCR7 during the Development of Innate and Adaptive αβT Cells in the Adult Thymus

αβT cell development depends upon serial migration of thymocyte precursors through cortical and medullary microenvironments, enabling specialized stromal cells to provide important signals at specific stages of their development. Although conventional αβT cells are subject to clonal deletion in the...

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Detalhes bibliográficos
Main Authors: Cowan, Jennifer E., McCarthy, Nicholas I., Parnell, Sonia M., White, Andrea J., Bacon, Andrea, Serge, Arnauld, Irla, Magali, Lane, Peter J. L., Jenkinson, Eric J., Jenkinson, William E., Anderson, Graham
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2014
Assuntos:
Immune System Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105241/
https://ncbi.nlm.nih.gov/pubmed/24990081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400993
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