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CCR7 Controls Thymus Recirculation, but Not Production and Emigration, of Foxp3(+) T Cells
Current models of Foxp3(+) regulatory T cell (Treg) development involve CCR7-mediated migration of thymocytes into the thymus medulla to enable essential interactions with medullary epithelium. However, increased Foxp3(+) thymic Treg numbers in Ccr7(−/−) mice challenge this view, and the role of CCR...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4751304/ https://ncbi.nlm.nih.gov/pubmed/26832402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.01.003 |
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