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Copper-catalyzed enantioselective 1,2-borylation of 1,3-dienes

A highly enantioselective Cu-catalyzed borylation of 2-substituted 1,3-dienes is reported. The use of a chiral phosphanamine ligand is essential in achieving high chemo-, regio-, diastereo- and enantioselectivity. It provides access to a variety of homoallylic boronates in consistently high yield an...

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Publicat a:Chem Sci
Autors principals: Liu, Yangbin, Fiorito, Daniele, Mazet, Clément
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001400/
https://ncbi.nlm.nih.gov/pubmed/29997884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc01538d
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