Adipocyte Xbp1s overexpression drives uridine production and reduces obesity

OBJECTIVE: The spliced transcription factor Xbp1 (Xbp1s), a transducer of the unfolded protein response (UPR), regulates lipolysis. Lipolysis is stimulated by fasting when uridine synthesis is also activated in adipocytes. METHODS: Here we have examined the regulatory role Xbp1s in stimulation of ur...

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Detaylı Bibliyografya
Yayımlandı:Mol Metab
Asıl Yazarlar: Deng, Yingfeng, Wang, Zhao V., Gordillo, Ruth, Zhu, Yi, Ali, Aktar, Zhang, Chen, Wang, Xiaoding, Shao, Mengle, Zhang, Zhuzhen, Iyengar, Puneeth, Gupta, Rana K., Horton, Jay D., Hill, Joseph A., Scherer, Philipp E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2018
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001360/
https://ncbi.nlm.nih.gov/pubmed/29551634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.02.013
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